Yes, it features professional-grade weather sealing and a fluorine coating on the front and rear elements to repel dust, water droplets, and grease.
Yes, it is fully compatible with Nikon Z6, Z7, Z8, and Z9 cameras when used with the Nikon FTZ or FTZ II mount adapter.
The 'E' version features an electromagnetic diaphragm for more accurate exposures during bursts and uses a lighter fluorite element, making it 110g lighter than the 'G' VR II version.