No, it is designed for Super 35 sensors. Using it on Full Frame cameras like the Sony Venice or Alexa LF will result in vignetting unless the camera is set to a Super 35 crop mode.
The lens has a standardized 95mm front diameter, which is consistent across most of the Ultra Prime series, allowing for fast accessory changes.
Yes, the fast T1.9 aperture allows for excellent performance in low-light environments and provides a shallow depth of field even at a wide 16mm focal length.