No, the Master Prime series is designed for Super 35 sensors. It will vignette on Full Frame sensors unless the camera is used in a Super 35 crop mode.
The lens has a standard 114mm front diameter, compatible with most professional matte boxes like the ARRI LMB-25.
Yes, the ultra-fast T1.3 aperture makes it one of the most capable lenses for shooting in low-light environments without sacrificing sharpness.